The Enzyme Experts
0
0
RNA Manufacturing

PSTR

mRNA cap-efficiency sample prep From 6 hours to <30 minutes

Download PDF

Submit
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Introduction

Cap-efficiency analysis shouldn't require hours of complex sample preparation.

See how RiboCleave™ 1 replaces a multistep RNase H-based workflow with one sequence-specific digestion, producing analysis-ready fragments in less than 30 minutes.

6 h → 30 min

Sample prep time

1

Digestion step

>80%

lower modeled cost per assay

Simplify mRNA cap-efficiency analysis

RiboCleave™ 1 uses one sequence-specific digestion to generate fragments for cap-efficiency analysis, supporting rapid screening during process development and high-resolution LC-MS analysis for QC.

Early access program

Test RiboCleave™ 1 in your own workflow

  • Early product access
  • Technical support from ArcticZymes specialists
  • Protocol guidance and workflow recommendations
  • Opportunity to provide feedback ahead of the full ISO batch production scheduled for 2027*

Early access offer

15% off

during the early access phase

Request early access

*Early access products are supplied for research use only. Formulation, recommended reaction conditions and specifications may change before full ISO release, following customer feedback collected during the early-access phase. We will notify early-access customers of any changes.

Relevant Resources

PTSR

Post-IVT template DNA removal with up to 10x fewer enzyme units

View more
PTSR
DNA fragment size determination

DNA fragment size determination: Are electrophoresis-based methods capable of detecting chromatin?

View more
PTSR
Purification of Measles Virus using Salt-active Nuclease

Purification of Measles Virus by Combination of Salt-active Nuclease Treatment and Heparin Affinity Chromatography

View more
PTSR

Endonuclease Treatment in Downstream Processing of Virus-Like Particles

View more
Lorem ipsum dolor

You're a scientist, so of course you have questions- Don't hesitate to contact us!